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You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know. Elias K. Current Protocols in Toxicology. Neurochemical Research. Methods in Molecular Biology Clifton, N. Journal of Neurochemistry. Ischemic tolerance in an in vivo model of glutamate preconditioning. Journal of Neuroscience Research. Oxaloacetate activates brain mitochondrial biogenesis, enhances the insulin pathway, reduces inflammation and stimulates neurogenesis.

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Gene expression patterns in the hippocampus during the development and aging of Glud1 Glutamate Dehydrogenase 1 transgenic and wild type mice. Bmc Neuroscience. Metabolism changes during aging in the hippocampus and striatum of glud1 glutamate dehydrogenase 1 transgenic mice.

Biochimica Et Biophysica Acta. Bioenergetic flux, mitochondrial mass and mitochondrial morphology dynamics in AD and MCI cybrid cell lines. DOI: Fluorogenic tagging of protein 3-nitrotyrosine with 4- aminomethyl benzene sulfonate in tissues: a useful alternative to Immunohistochemistry for fluorescence microscopy imaging of protein nitration. Asn Neuro.

Neuronal Glud1 glutamate dehydrogenase 1 over-expressing mice: increased glutamate formation and synaptic release, loss of synaptic activity, and adaptive changes in genomic expression. Neurochemistry International.

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Functional genomics of brain aging and Alzheimer's disease: focus on selective neuronal vulnerability. Current Genomics. Selective neuronal vulnerability to oxidative stress in the brain. Frontiers in Aging Neuroscience.

Transcriptomic responses in mouse brain exposed to chronic excess of the neurotransmitter glutamate. Bmc Genomics. Transgenic expression of Glud1 glutamate dehydrogenase 1 in neurons: in vivo model of enhanced glutamate release, altered synaptic plasticity, and selective neuronal vulnerability. Integrating multiple microarray data for cancer pathway analysis using bootstrapping K-S test. Genomic and biochemical approaches in the discovery of mechanisms for selective neuronal vulnerability to oxidative stress.

A rat brain bicistronic gene with an internal ribosome entry site codes for a phencyclidine-binding protein with cytotoxic activity. The Journal of Biological Chemistry. Genome-wide transcriptome profiling of region-specific vulnerability to oxidative stress in the hippocampus. The Biochemical Journal. Decreased activity and increased aggregation of brain calcineurin during aging. Brain Research. High intrinsic oxidative stress may underlie selective vulnerability of the hippocampal CA1 region. Molecular Brain Research. Selective dendrite-targeting of mRNAs of NR1 splice variants without exon 5: identification of a cis-acting sequence and isolation of sequence-binding proteins.

Superoxide modification and inactivation of a neuronal receptor-like complex. Chronic ethanol exposure increases gene transcription of subunits of an N-methyl-D-aspartate receptor-like complex in cortical neurons in culture. Neuroscience Letters. Activity-dependent nitric oxide concentration dynamics in the laterodorsal tegmental nucleus in vitro. Journal of Neurophysiology. Immunocytochemical and in situ hybridization studies of the expression and distribution of three subunits of a complex with N-methyl-D-aspartate receptor-like properties.

Elias K. Michaelis - Publications

Calcium influx through NMDA receptors, chronic receptor inhibition by ethanol and 2-aminophosponopentanoic acid, and receptor protein expression. Biochemical and Biophysical Research Communications. Molecular biology of glutamate receptors in the central nervous system and their role in excitotoxicity, oxidative stress and aging.


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Progress in Neurobiology. Protein half-lives of calmodulin and the plasma membrane Ca-ATPase in rat brain.


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L-glutamate and N-methyl-D-aspartate receptors: learning, growth, and death in the mammalian brain. A synaptic membrane glycine-, glutamate- and thienylcyclohexylpiperidine-binding protein: isolation and immunochemical characterization. Febs Letters. The 71 kDa glutamate-binding protein is increased in cerebellar granule cells after chronic ethanol treatment.

Ethanol-induced inhibition of [3H]thienylcyclohexylpiperidine TCP binding to NMDA receptors in brain synaptic membranes and to a purified protein complex. Cloning of the cDNA for a brain glycine-, glutamate- and thienylcyclohexylpiperidine-binding protein. Direct measurement of glutamate release in the brain using a dual enzyme-based electrochemical sensor. Alcoholism, Clinical and Experimental Research.

Two different families of NMDA receptors in mammalian brain: physiological function and role in neuronal development and degeneration. Advances in Experimental Medicine and Biology.

Biochemical Pharmacology notes PDF ebook for Medical students

Immunochemical and immunohistochemical characterization of a synaptic membrane protein that binds the competitive antagonists of NMDA receptors. Glutamate receptor changes in brain synaptic membranes during chronic alcohol intake. Alcohol and Alcoholism Oxford, Oxfordshire. Characterization of organophosphate interactions at N-methyl-D-aspartate receptors in brain synaptic membranes.

Molecular Pharmacology. Purification, reconstitution, and cloning of an NMDA receptor-ion channel complex from rat brain synaptic membranes: implications for neurobiological changes in alcoholism.


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